The Australian, By Tony Kirby, 31 July 2010
“The dilemma of whether to take a diagnostic test for the Huntington’s disease gene is one that affects thousands of families in Australia. Moreover, should the test results be positive, that person’s life, including family planning, becomes very complex. For instance, Bridget, in her early 30s, found out about seven years ago that her mother, Judy, now in her 60s, had HD. “I move in and out of denial,” says Bridget. On another front, pre-implantation genetic diagnosis has transformed reproductive choices about genetic conditions such as HD and cystic fibrosis. In PGD, several embryos are created and one without the HD gene is chosen for implantation using in-vitro fertilisation treatment. While this ensures the child won’t have the HD gene, it doesn’t guarantee a successful IVF pregnancy. Multiple IVF cycles may be required, so extra embryos are frozen in case they’re needed.”
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